"The Family Research Institute (FRI), originally known as the Institute for the Scientific Investigation of Sexuality (ISIS), is an American socially conservative non-profit organization based in Colorado Springs, Colorado which states that it has "...one overriding mission: to generate empirical research on issues that threaten the traditional family, particularly homosexuality, AIDS, sexual social policy, and drug abuse". The FRI is part of a sociopolitical movement of socially conservative Christian organizations which seek to influence the political debate in the United States. They seek "...to restore a world where marriage is upheld and honored, where children are nurtured and protected, and where homosexuality is not taught and accepted, but instead is discouraged and rejected at every level." The Boston Globe reported that the FRI's 2005 budget was less than $200,000.

The FRI is led by Paul Cameron, who received a doctorate in psychology from the University of Colorado at Boulder in 1966. Cameron founded the Institute for the Scientific Investigation of Sexuality in 1982, and this institute later became the FRI.

The Family Research Institute has been designated an anti-gay hate group by the Southern Poverty Law Center since 2006 because of Cameron's discredited research and claims about LGBT people."